Non-invasive Electrical Source Imaging for Localizing Epileptiform Discharges in Children with Focal Epilepsy Based on Developing Country’s Limitations

Background: Preliminary studies have shown that electrical source imaging (ESI) has numerous advantages for the pre-surgical evaluation of epileptic patients. However, role ESI children with non-lesional drug resistance in focal epilepsy been poorly characterized. Objectives: This study aimed to investigate this issue according interictal epileptiform discharges (IEDs) and constraints developing countries. Methods: The present used long-term video electroencephalography (EEG) monitoring (LTM) data were recorded using standard 19 scalp electrodes (10 - 20 system) 3 tesla T1 image data. Accordingly, first, IEDs clustered then assessed by an epileptologist. Afterward, some operations conducted included EEG inverse problem solving three known methods, namely brain analysis (BESA) individual head model, cortical classical LORETA recursively (CLARA) BESA age template model. Seven processed project. Results: In most cases (n = 5, 71%), seizure onset zone (SOZ) was same LTM report proposed methodology. Moreover, succeeded localizing region predicted SOZ. Conclusions: According limitations a country, configuration multi-modal (e.g., 3T magnetic resonance imaging, LTM, ESI) specific valuable protocol, investigation defined pilot 7 sample first step. These findings, based on small size, suggest combining ensemble methods improves information drug-resistant epilepsy. It is hoped future large sizes show countries more than before.